𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Conversion of ribonucleosides to protected 3′-deoxynucleosides

✍ Scribed by Kelvin K. Ogilvie; Gholam H. Hakimelahi; Zbigniew A. Proba; Nassim Usman

Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
187 KB
Volume
24
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

A procedure is presented for the conversion of ribonucleosides to 3'-deoxyribonucleosides and their protected derivatives.

📜 SIMILAR VOLUMES

High-yield synthesis of 3′-amino-3′-deox
High-yield synthesis of 3′-amino-3′-deoxynucleosides. Conversion of adenosine to 3′-amino-3′-deoxyadenosine
✍ Mirna C. Samano; Morris J. Robins 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 277 KB

A S-O-silylated-2',3'-anhydroadenosine derivative underwent epoxide opening smoothly with dimethylboron bromide. The N-benzyl carbamate derived from the trans bromohydrin was ring-closed with sodium hydride. Deprotection (fluoride, hydroxide, and hydrogenolysis) gave 3'-amino-3'-deoxyadenosine (6)

Chemoenzymatic Synthesis of 3′-O-Acetal-
Chemoenzymatic Synthesis of 3′-O-Acetal-Protected 2′-Deoxynucleosides as Building Blocks for Nucleic Acid Chemistry
✍ Tatiana Rodríguez-Pérez; Susana Fernández; Saúl Martínez-Montero; Tania González 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 217 KB

## Abstract We have developed a simple and convenient synthetic strategy for the preparation of tetrahydropyranyl, 4‐methoxytetrahydropyranyl, and tetrahydrofuranyl ethers of 2′‐deoxynucleosides, which are useful building blocks for nucleic acid chemistry. Enzymatic benzoylation provides an efficie

Nucleosides and Nucleotides. Part 17. A
Nucleosides and Nucleotides. Part 17. A simple preparation of protected deoxynucleoside-3'-phosphates
✍ Silvio Bernardini; Felix Waldmeier; Christoph Tamm 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 German ⚖ 415 KB

## Abstract A simple method for the preparation of fully protected 2′‐deoxynucleoside‐3′‐phosphates is described. The main step, phosphorylation of partially protected deoxynucleosides, is performed with the monofunctional reagent __p__‐chlorophenyl (2‐cyanoethyl) phosphochloridate^3^) (**2**) in d