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A reasonably stereospecific multistep conversion of Boc-protected α-amino acids to Phth-protected β3-amino acids

✍ Scribed by Andrea Temperini; Antonella Capperucci; Alessandro Degl’Innocenti; Raffaella Terlizzi; Marcello Tiecco


Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
809 KB
Volume
51
Category
Article
ISSN
0040-4039

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A new approach to β-amino acids: biotran
✍ Margit Preiml; Kerstin Hillmayer; Norbert Klempier 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 79 KB

A number of novel N-protected b-amino nitriles were prepared as substrates for two nitrile-converting microorganisms, Rhodococcus sp. R312 and Rhodococcus erythropolis NCIMB 11540. The respective biotransformation products, b-amino acids, are known to be pharmacological very potent compounds.