A new approach to β-amino acids: biotransformation of N-protected β-amino nitriles

✍ Scribed by Margit Preiml; Kerstin Hillmayer; Norbert Klempier

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 79 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)01136-5

✦ Synopsis

A number of novel N-protected b-amino nitriles were prepared as substrates for two nitrile-converting microorganisms, Rhodococcus sp. R312 and Rhodococcus erythropolis NCIMB 11540. The respective biotransformation products, b-amino acids, are known to be pharmacological very potent compounds.