𝔖 Bobbio Scriptorium
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Conversion of oxindole alkaloids into indole alkaloids

✍ Scribed by Norio Aimi; Etsuji Yamanaka; Jyunji Endo; Shin-ichiro Sakai; Joju Haginiwa


Publisher
Elsevier Science
Year
1972
Tongue
French
Weight
231 KB
Volume
13
Category
Article
ISSN
0040-4039

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Indole alkaloids of the iboga series were structurally modified by incorporation of a 3,4-dimethoxybenzyl or -benzoyl unit so that they contained the N-O-O triangle required for antileukemic activity according to the triangulation hypothesis. The cytotoxicities of the modified alkaloids in the in vi

X-Ray Crystal Structure Analysis of Oxin
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## Abstract The single‐crystal X‐ray structures of speciophylline, mitraphylline, and rhynchophylline, oxindole alkaloids from the Peruvian climbing vine __Uncaria tomentosa__ (Rubiaceae), were determined. The three compounds show Nβ‹…β‹…β‹…Hο£ΏN hydrogen bonding, which has not been observed in the crystal