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Conversion of ‘obstinate’ nitriles to amidines by Garigipati's reaction

✍ Scribed by Robert A. Moss; Wei Ma; Dina C. Merrer; Song Xue

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
395 KB
Volume
36
Category
Article
ISSN
0040-4039

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An efficient conversion of nitriles to a
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✍ Ravi S. Garigipati 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 185 KB

A convenient method has been developed for direct conversion of nitriles to amidines in high yields; The method can also be applied to the preparation of guanidines from N-alkyl cyanamides. An efficient one step preparation of an amidine by the direct nucleophilic addition of an amine to the parent

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✍ Roger W. Binkley 📂 Article 📅 1970 🏛 Elsevier Science 🌐 French ⚖ 90 KB

The synthesis of nitriles is a process which, in the past, has frequently required quite n vigorous reaction conditions'. In recent years, however, interest has arisen in examining milder methods for nitrile synthesis 3-5 . As a contribution to the solution of this problem of reaction conditions, w