High-performance liquid chromatographic
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Nobumitsu Hanioka; Hideto Jinno; Tetsuji Nishimura; Masanori Ando; Shogo Ozawa;
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Article
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2001
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John Wiley and Sons
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English
โ 116 KB
๐ 1 views
## Abstract A simple and sensitive assay for glucuronidation activity of 7โethylโ10โhydroxycamptothecin (SNโ38), the active metabolite of irinotecan (CPTโ11), in human liver microsomes by highโperformance liquid chromatography (HPLC) with fluorescence detection is reported. The method was validated