๐”– Bobbio Scriptorium
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Conversion of Alcohols to Thiols via Tosylate Intermediates.

โœ Scribed by Arthur W. Snow; Edward E. Foos


Book ID
101944968
Publisher
John Wiley and Sons
Year
2003
Weight
110 KB
Volume
34
Category
Article
ISSN
0931-7597

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A new, highly efficient method for the c
โœ R.P. Volante ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 176 KB

Various alcohols were converted to their corresponding thiolacetates by treatment with triphenylphosphine and diisopropyl azodicarboxylate in the presence of thiolacetlc acid. The overall conversion was both highly efficient (89-99X yields) and stereoselective (99.5% inversion).