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Conversion of 3-hydroxy-1,2,3,4-tetrahydroquinoline-2,4-diones to 2,3a,4,5-tetrahydrofuro[2,3-c]quinoline-2,4-diones via an intramolecular wittig reaction

✍ Scribed by Antonín Klásek; Stanislav Kafka

Publisher: Journal of Heterocyclic Chemistry
Year: 1998
Tongue: English
Weight: 321 KB
Volume: 35
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570350208

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✦ Synopsis

Abstract

The preparation of 2,3a,4,5‐tetrahydrofuro[2,3‐c]quinoline‐2,4‐diones starting from 3‐hydroxy‐1,2,3,4‐tetrahydroquinoline‐2,4‐diones and using the reaction path via bromoacetylderivatives and triphenylphosphonioacetyl derivatives of the initial substances is described. The nmr spectra of the products are discussed.

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