Convergent stereospecific total synthesi
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Isabelle Tichkowsky; Robert Lett
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Article
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2002
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Elsevier Science
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French
β 304 KB
A much improved and reliable access to the macrolide 9, key-intermediate in our synthesis of monocillin I and radicicol is reported, via a modification of our first synthesis. The formation of the conjugated E,Z-dienone trans-epoxide is now achieved in a much higher yield, in a stereospecific reacti