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Convenient synthesis of some new pyrazolo[1,5-a]pyrimidine, pyridine, thieno[2,3-b]pyridine, and isoxazolo[3,4-d]pyridazine derivatives containing benzofuran moiety

✍ Scribed by Abdou O. Abdelhamid

Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
149 KB
Volume
46
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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Pyrazolo[1,5‐a]pyrimidines, pyrazoles, and thieno[2,3‐b]pyridine were synthesized from sodium salt of 5‐benzofuran‐2‐yl‐3‐hydroxypropenone and the appropriate of heterocyclic amines, diazonium chloride, and 1,3‐dicarbonoyl compounds. Pyrimidino[4′,5′:4,5]thieno[2,3‐b]pyridine, 1,2,3,4‐tetrazolo[1″,5″:6′,1′]‐pyrimidino[4′,5′:4,5]thieno[2,3‐b]pyridine and pyridino[2″,3″:2′,3′]thieno[4,5‐d]1,2,4‐triazolo[4,3‐e]pyrimidine derivatives were synthesized from 6‐benzo[d]furan‐2‐yl‐2‐thioxohydropyridine‐3‐carbonitrile and each of formic acid or formamide. Structures of the newly synthesized were established by elemental analysis and spectral data. J. Heterocyclic Chem. (2009).

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Synthesis of new pyrazolo[1,5-a]pyrimidi
Synthesis of new pyrazolo[1,5-a]pyrimidines and pyrazolo[3,4-b]pyridines
✍ Saleh M. Al-Mousawi; Mohammad A. Mohammad; Mohamad H. Elnagdi 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 29 KB 👁 1 views

## Abstract While 3(5)‐aminopyrazole reacts with enaminonitrile to yield pyrazolo[1,5‐__a__]pyrimidines, 3‐amino‐5‐pyrazolone reacts with the same reagents to yields pyrazolo[3,4‐__b__]pyridines.