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Convenient synthesis of 4-amino-7-(dialkylamino)pyrido[2,3-d]pyrimidines from polysubstituted pyridines

โœ Scribed by Maria Teresa Cocco; Cenzo Congiu; Antonio Maccioni; Valentina Onnis

Book ID
112130576
Publisher
Journal of Heterocyclic Chemistry
Year
1993
Tongue
English
Weight
193 KB
Volume
30
Category
Article
ISSN
0022-152X

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A convenient synthesis of trisubstituted
A convenient synthesis of trisubstituted pyrido[2,3-d]pyrimidin-7-ones
โœ Jiri Kasparec; Jerry L. Adams; Joseph Sisko; Domingos J. Silva ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 99 KB

A novel, highly efficient and scalable route for the synthesis of trisubstituted pyrido[2,3-d]pyrimidin-7-ones was developed. The target compounds were synthesized in five steps from readily available reagents in about 40% overall yield.