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Convenient routes to 2-aryl-2-fluoropropionic acids: Synthesis of monofluorinated analogues of (±)-ibuprofen, (±)-naproxen and related compounds

✍ Scribed by Olav Goj; Sirpa Kotila; Günter Haufe


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
923 KB
Volume
52
Category
Article
ISSN
0040-4020

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The First Synthesis of Azapterocarpans a
✍ Tőkés, Adrienne L. ;Antus, Sándor 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 487 KB

## Abstract The first synthesis of the 5,6,6a,11a‐tetrahydro[1]benzofuro[3,2‐__c__]quinolines (5‐azapterocarpans) 1–4 has been achieved by palladium‐catalyzed arylation of the appropriately substituted 1,2‐dihydroquinolines 15, 16. The 5‐azapterocarpans 3 and 4 have been transformed into the 3‐aryl