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Convenient Procedure of Horner—Wadsworth—Emmons Olefination for the Synthesis of Simple and Functionalized α,β-Unsaturated Nitriles.

✍ Scribed by Alessandra Lattanzi; Liliana R. Orelli; Patrizia Barone; Antonio Massa; Patrizia Iannece; Arrigo Scettri


Book ID
111699525
Publisher
John Wiley and Sons
Year
2003
Weight
206 KB
Volume
34
Category
Article
ISSN
0931-7597

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📜 SIMILAR VOLUMES


Convenient procedure of Horner–Wadsworth
✍ Alessandra Lattanzi; Liliana R. Orelli; Patrizia Barone; Antonio Massa; Patrizia 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 799 KB

A mild and practical procedure of Horner-Wadsworth-Emmons olefination promoted by lithium hydroxide and a-cyano phosphonates has been set up for the synthesis of a,b-unsaturated nitriles. The reaction conditions are tolerated by functionalized ketones and the exclusive formation of E-g-hydroxy a,b-u

Enantioselective Horner–Wadsworth–Emmons
✍ Shigeki Sano; Kenji Yokoyama; Rie Teranishi; Motoo Shiro; Yoshimitsu Nagao 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 106 KB

The enantioselective Horner-Wadsworth-Emmons reaction of 2-fluoro-2-diethylphosphonoacetates with s-symmetric prochiral 2-substituted-1,3-dioxan-5-ones and 4-substituted-cyclohexanones was investigated by employing Sn(OSO 2 CF 3 ) 2 and N-ethylpiperidine in the presence of an external chiral ligand,