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Convenient one-pot multicomponent strategy for the synthesis of 6-pyrrolylpyrimidines

✍ Scribed by Dhanalakshmi, Pandi; Shanmugam, Sivakumar


Book ID
126767064
Publisher
The Royal Society of Chemistry
Year
2014
Tongue
English
Weight
522 KB
Volume
4
Category
Article
ISSN
2046-2069

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ChemInform Abstract: A Convenient One-Po
✍ I. KATSUYAMA; S. OGAWA; H. NAKAMURA; Y. YAMAGUCHI; K. FUNABIKI; M. MATSUI; H. MU πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 35 KB πŸ‘ 1 views

Reaction of Ξ±,Ξ²-unsaturated trifluoromethyl ketones (I) with primary enamines in the presence of POCl 3 and pyridine adsorbed on silica gel and following oxidation of the resulting dihydropyridines provides a high-yielding synthesis of title compounds (III) (16 examples). -(KATSUYAMA, I.; OGAWA,