## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
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Convenient Acylative Dealkylation of Tertiary Amines
β Scribed by Dave, Paritosh R.; Kumar, Kaipenchery A.; Duddu, Rajagopal; Axenrod, Theodore; Dai, Rongji; Das, Kajal K.; Guan, Xiao-Pei; Sun, Jianguang; Trivedi, Nirupam J.; Gilardi, Richard D.
- Book ID
- 126075736
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 44 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3263
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Phenyl chlorothionoformate reacts rapidly with aliphatic amines at 20Β°C to give a thiourethane and an alkyl chloride. The urethanes are readily converted to the secondary amine salt by reaction with dimethyl sulfate, followed by hydrolysis with water. Rates of reaction, and alkyl group cleavage sele