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Controlled release of anticancer drugs from collagen-poly(HEMA) hydrogel matrices

✍ Scribed by R. Jeyanthi; K.Panduranga Rao


Book ID
119133890
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
733 KB
Volume
13
Category
Article
ISSN
0168-3659

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Drug release from collagen matrices is in most cases governed by diffusion from swollen matrices but also enzymatic matrix degradation or hydrophobic drug/collagen interactions may contribute. To reduce water uptake and to prolong the release, insoluble collagen matrices have been chemically or dehy