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Controlled Drug Release of Highly Water-Soluble Pentoxifylline from Time-Limit Disintegration-Type Wax Matrix Tablets

โœ Scribed by Makoto Otsuka; Yoshihisa Matsuda


Book ID
110379895
Publisher
Springer US
Year
1994
Tongue
English
Weight
558 KB
Volume
11
Category
Article
ISSN
0724-8741

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โœ Venkatramana M. Rao; John L. Haslam; Valentino J. Stella ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 244 KB ๐Ÿ‘ 1 views

Sustained-release formulations such as hydroxypropyl methylcellulose (HPMC)based hydrophilic matrix tablets of poorly water-soluble drugs often result in incomplete release because of the poor solubility and dissolution rate of the drug in the hydrophilic matrix. Sulfobutylether-b-cyclodextrins ((SB