Controlled Drug Release from Self-Catalyzed Poly(Ortho Esters)
โ Scribed by STEVEN Y. NG; THIERRY VANDAMME; MICHELLE S. TAYLOR; JORGE HELLER
- Book ID
- 111393418
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 443 KB
- Volume
- 831
- Category
- Article
- ISSN
- 0890-6564
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๐ SIMILAR VOLUMES
A polyblend of poly(ortho esters)-poly(ethylene glycol) (POE-PEG) was prepared. The release behavior of the acetanilide-loaded film of the POE-PEG polyblend was studied. Blending POE with water-soluble PEG can promote the release of drug in pH 7.4 PBS buffer at 37ยฐC, while POE has plasticizing effec
Semisolid, self-catalyzed poly(ortho ester)s (POEs), are investigated as potential sustained-release systems for proteins. In this study, some factors influencing protein release kinetics and protein instability were evaluated. As model proteins, lysozyme, alpha-lactalbumin, bovine serum albumin, an