𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Drug release from poly(ortho esters)–poly(ethylene glycol) polyblend

✍ Scribed by Min Wei; Jin Chang; Kang De Yao; Steven Ng; Jorge Heller

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
307 KB
Volume
71
Category
Article
ISSN
0021-8995

No coin nor oath required. For personal study only.

✦ Synopsis

A polyblend of poly(ortho esters)-poly(ethylene glycol) (POE-PEG) was prepared. The release behavior of the acetanilide-loaded film of the POE-PEG polyblend was studied. Blending POE with water-soluble PEG can promote the release of drug in pH 7.4 PBS buffer at 37°C, while POE has plasticizing effect on PEG. Infrared and X-ray diffraction studies reveal that there is some interaction between POE and acetanilide. The SEM micrographs disclose that the porosity of the drug-loaded film enhances with an increase immersing time.

📜 SIMILAR VOLUMES

Preparation and drug-release behavior of
Preparation and drug-release behavior of minocycline-loaded poly[hydroxyethyl methacrylate-co-poly(ethylene glycol)–methacrylate] films
✍ Gülay Bayramoğlu; Ertan Batislam; M. Yakup Arica 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB

## Abstract In this work, biocompatible hydrogel matrices for wound‐dressing materials and controlled drug‐release systems were prepared from poly[hydroxyethyl methacrylate‐__co__‐poly(ethylene glycol)–methacrylate] [p(HEMA‐__co__‐PEG–MA] films via UV‐initiated photopolymerization. The characteriza

Lithium ionic conductivity in poly(ether
Lithium ionic conductivity in poly(ether urethanes) derived from poly(ethylene glycol) and lysine ethyl ester
✍ K. V. Ramanujachary; X. Tong; Y. Lu; J. Kohn; M. Greenblatt 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB 👁 1 views

Poly(ether urethanes) obtained by the copolymerization of poly(ethylene glycol) (PEG) and lysine ethyl ester (LysOEt) are elastomeric materials that can be processed readily to form flexible, soft films. In view of these desirable physicomechanical properties, the potential use of these new material

Hydrogels of modified ethylenediaminetet
Hydrogels of modified ethylenediaminetetraacetic dianhydride gelatin conjugated with poly(ethylene glycol) dialdehyde as a drug-release matrix
✍ G. V. N. Rathna 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB

## Abstract Hydrogels have been recognized as versatile biomaterials in biomedical applications. This article describes the synthesis and characterization of a poly(ethylene glycol) (PEG) dialdehyde derivative, the modification of gelatin with ethylenediaminetetraacetic dianhydride (EDTAD), and the