Functional deficits following traumatic brain injury (TBI) are associated with alterations in markers of dopaminergic neurotransmission. To assess the effects of TBI on the expression and functional integrity of dopamine transporters, we measured transporter protein levels and investigated synaptoso
β¦ LIBER β¦
Controlled cortical impact injury affects dopaminergic transmission in the rat striatum
β Scribed by A. K. Wagner; J. E. Sokoloski; D. Ren; X. Chen; A. S. Khan; R. D. Zafonte; A. C. Michael; C. E. Dixon
- Book ID
- 111179135
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 488 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0022-3042
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## Abstract Traumatic brain injury is followed by increased extracellular glutamate concentration. Uptake of glutamate is mainly mediated by the glial glutamate transporters GLAST and GLTβ1. Extent and distribution of GLAST and GLTβ1 were studied in a rat model of controlled cortical impact injury