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Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

✍ Scribed by Quintana, Francisco J.; Basso, Alexandre S.; Iglesias, Antonio H.; Korn, Thomas; Farez, Mauricio F.; Bettelli, Estelle; Caccamo, Mario; Oukka, Mohamed; Weiner, Howard L.

Book ID: 109897387
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 826 KB
Volume: 453
Category: Article
ISSN: 0028-0836
DOI: 10.1038/nature06880

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## Abstract Regulatory T (T~reg~) cells play a key role in the maintenance of the immune system homeostasis. T~reg~ cells can be generated in the periphery under control of TGF‐β, a cytokine involved in the negative control of the immune system. However, TGF‐β cooperates with IL‐6 in the generation