Reciprocal generation of Th1/Th17 and Treg cells by B1 and B2 B cells
✍ Scribed by Xuemei Zhong; Wenda Gao; Nicolas Degauque; Chunyan Bai; Yan Lu; James Kenny; Mohamed Oukka; Terry B. Strom; Thomas L. Rothstein
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 195 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Dendritic cells are the most relevant antigen-presenting cells (APC) for presentation of antigens administered in adjuvant to CD4 + T cells. Upon interaction with antigen-specific T cells, dendritic cells (DC) expressing appropriate peptide-MHC class II complexes secrete IL-12, a cytokine that drive
## Abstract ## Objective HLA–B27/human β~2~‐microglobulin–transgenic (B27‐transgenic) rats, a model of spondylarthritis (SpA), develop spontaneous colitis and arthritis under conventional conditions. CD4+ T cells are pivotal in the development of inflammation in B27‐transgenic rats. This study was
## Abstract The cytokine IL‐7 and its receptor are essential for normal B and T lymphopoiesis. We have analyzed the role of this receptor in B cell development throughout ontogeny in IL‐7 receptor α‐deficient mice. We demonstrate that the IL‐7 receptor becomes progressively more important with age.