Control of plasma 1,25-(OH)2-vitamin D concentrations by calcium and phosphorus in the rat: Effects of hypophysectomy
โ Scribed by Richard W. Gray
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 320 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1432-0827
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๐ SIMILAR VOLUMES
1,25-dihydroxy-vitamin D(3) (1,25(OH)(2)D(3)), the hormonally active form of vitamin D(3), acts through two different mechanisms. In addition to regulating gene expression via the specific intracellular vitamin D receptor (VDR), 1,25(OH)(2)D(3) induces rapid, non-transcriptional responses involving
The plasma disappearance rate of 1,25-dihydroxyvitamin D3 [ 1,25-(OH)\*D3] was determined in rats after a single intravenous injection of the tritiated hormone. Tritiated 1,25-(OH)2D3 (120 Ci mmol-I) was administered to rats at a dose of 400 000 dpm kg-' body weight and the animals were bled between