Control of methionine biosynthesis genes by protein kinase CK2-mediated phosphorylation of Cdc34
β Scribed by T. Barz; K. Ackermann; W. Pyerin
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 312 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1420-682X
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Nuclear matrix (NM), a proteinaceous network of filaments, dictates nuclear morphology and the structure/function of DNA. Phosphorylation of NM proteins is a potential signal for regulating matrix functions. Histones also are intimately involved in DNA structure and transcription. Here, we report th
## Abstract We have investigated the role of phosphorylation by vertebrate protein kinase CK2 on the activity of the General Transcription Factors TFIIA, TFIIE, TFIIF, and RNAPII. The largest subunits of TFIIA, TFIIE, and TFIIF were phosphorylated by CK2 holoenzyme. Also, RNA polymerase II was phos