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Control of macromolecular synthesis in proliferating and resting syrian hamster cells in monolayer culture. II. Ribosome complement in resting and early G1 Cells

✍ Scribed by H. Becker; C. P. Stanners; J. E. Kudlow

Publisher: John Wiley and Sons
Year: 1971
Tongue: English
Weight: 624 KB
Volume: 77
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040770106

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✦ Synopsis

Abstract

Using a new, sensitive and quantitative technique for determining the ribosomal‐RNA content of a measured number of cells, the cellular ribosome complement was compared for cultured hamster embryo cells in the stationary growth phase and in the early G~1~ phase of the cell cycle. Cells from stationary phase cultures were found to contain less than 70% of the ribosome complement of the early G~1~ phase cells, though the volumes of the two cell types were similar. This would imply that the stationary phase cell is physiologically different from a cell merely arrested at some point in the cell cycle.

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