Control of hyperglycemia of diabetic rats by parabiosis with normal rats
β Scribed by Weitze, Marie ;Higgins, George M.
- Publisher
- John Wiley and Sons
- Year
- 1954
- Tongue
- English
- Weight
- 578 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0003-276X
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In one of our earlier studies, an impaired biliary function in diabetes was suggested. We studied bile formation in rats with streptozotocin-induced diabetes (60 mg per kg body weight). Diabetic rats showed hyperglycemia and hypoinsulinemia, but no significant changes in hematocrit, plasma protein c
The effects of synthetic rat C-peptide 1 and C-peptide 2 on plasma insulin and blood glucose concentrations in the rat were studied. Infusion of rat C-peptide (500 micrograms X h-1 X kg-1) diminished glucose induced increase of plasma insulin by 56% (15.2 +/- 0.9 versus 6.6 +/- 0.6 ng/ml, p less tha
## Abstract Diabetes mellitus has been shown to alter the properties of bone and impair fracture healing in both humans and animals. The objective of this study was to document changes in the structural and material properties of intact bone and bone with healed fractures in diabetic rats compared