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Control of homozygous β-thalassemia by carrier screening and antenatal diagnosis in Sardinians

✍ Scribed by A. Cao; L. P<sc>intus; U. Lecca; G. Oixa; P. Cossu; C. Rosatelli; R. Galanello


Book ID
119839570
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
684 KB
Volume
26
Category
Article
ISSN
0009-9163

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Molecular screening and fetal diagnosis
✍ Maria Cristina Rosatelli; Teresa Tuveri; Maria Teresa Scalas; Giovan Battista Le 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 455 KB

This paper reports our experience of molecular screening and fetal diagnosis of beta-thalassemia in 457 at risk couples of Italian descent. Molecular screening was carried out by dot blot analysis on amplified DNA with oligonucleotide probes complementary to the eight most common mutations in Italia