Control of early stages in invariant natural killer T-cell development
✍ Scribed by Taishan Hu; Idoia Gimferrer; José Alberola-Ila
- Book ID
- 108782918
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 368 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0019-2805
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During the past year, there have been rapid advances in our understanding of the early events of T-cell development, at the molecular level. Studies at the transcriptional level of T-cell receptor gene regulation have started to yield important clues about how different T-cell-specific genes can sha
## Abstract ## Objective To investigate the role of invariant natural killer T (iNKT) cells in TNF^__ΔARE/+__^ mice, an animal model of spondylarthritis (SpA) with both gut and joint inflammation. ## Methods The frequency and activation of iNKT cells were analyzed on mononuclear cells from the l