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Control of DNA polymerase λ stability by phosphorylation and ubiquitination during the cell cycle

✍ Scribed by Wimmer, Ursula; Ferrari, Elena; Hunziker, Peter; Hübscher, Ulrich


Book ID
109850079
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
592 KB
Volume
9
Category
Article
ISSN
1469-221X

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## Abstract The carboxyl‐terminal domain (CTD) of the largest subunit of mammalian RNA polymerase II (RNAP II) consists of 52 repeats of a consensus heptapeptide and is subject to phosphorylation and dephosphorylation events during each round of transcription. RNAP II activity is regulated during t