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Control of dissolved oxygen concentration in mammalian cell culture using a computer-coupled mass flow controller

โœ Scribed by Heung C. Jung; Deok K. Oh; Jung H. Kim

Book ID
105578591
Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
200 KB
Volume
6
Category
Article
ISSN
0951-208X

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The performances of three types of cell mass control algorithms were tested experimentally in a continuous stirred tank biological reactor (CSTBR). While the performance of the PID controller was undesirable and parameter tuning was not easy, the Extended Least-squares Self-tuning Regulator (ELS-STR