Computer control of cell mass concentration in continuous culture

✍ Scribed by Gyeongbeom Yi; Young Bo Hwang; Ho Nam Chang; Kwang Soon Lee

• Book ID: 102637407
• Publisher: Elsevier Science
• Year: 1989
• Tongue: English
• Weight: 418 KB
• Volume: 25
• Category: Article
• ISSN: 0005-1098
• DOI: 10.1016/0005-1098(89)90077-0

✦ Synopsis

The performances of three types of cell mass control algorithms were tested experimentally in a continuous stirred tank biological reactor (CSTBR). While the performance of the PID controller was undesirable and parameter tuning was not easy, the Extended Least-squares Self-tuning Regulator (ELS-STR) and a Bilinear Model Adaptive Controller (BMAC) indicated excellent performances. Especially, the BMAC, based on a nonlinear predictor model with only one parameter to be identified, showed less excessive fluctuation of control action and better adaptation performance over the ELS-STR.