The synthesis of t h e title canpound (7) is described. [2-14C] cytosine (I) is treated with an aqueous mixture of sodium bisulfite and sodium sulfate at 8OoC for 30 rnin. The resulting solid is then treated with aqueous sodiun hydroxide and passed through a cation exchange colunn, producing [ Z-14C
✦ LIBER ✦
Contribution to the synthesis of 2-deoxy-D-ribose-1−14C
✍ Scribed by V. Soukupová; K. Vereš
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- French
- Weight
- 299 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
For introducing 14C into position I of 2-deoxyaldoses, methods based on prolongation of the carbon chain usually come into consideration since one can proceed from simple and inexpensive 14C-compounds. Such a possibility is ofleered by the method of Fisher and
Sowden'l? 2, which was applied by a number of other authors. I C H, NO, C H NO, CHI NO,
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