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Contribution of phosphodiesterase isoenzymes and cyclic nucleotide efflux to the regulation of cyclic GMP levels in aortic smooth muscle cells

✍ Scribed by Javier Mercapide; Esteban Santiago; Elena Alberdi; Juan J. Martinez–Irujo


Book ID
113994583
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
416 KB
Volume
58
Category
Article
ISSN
0006-2952

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The cyclic nucleotides cyclic adenosine monophosphate (CAMP) and cyclic guanosine monophosphate (cGMP) are second messengers involved in the regulation of contractility in various smooth muscle organs including detrusor smooth muscle. They are synthesized by activation of adenylate and guanylate cyc