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Contribution of oral magnetic particles in MR imaging of the abdomen with spin-echo and gradient-echo sequences

✍ Scribed by Frank P. Boudghëne; Torre Bach-Gansmo; Jean-Didier Grange; Samuel Lame; Christine Nantois; Claudy Wallays; Jean-Michel Bigot

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
688 KB
Volume
3
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

An open phase III clinical trial of the oral contrast agent OMP (oral magnetic particles) was performed in 35 patients undergoing abdominal magnetic resonance (MR) imaging at 1.5 T with axial spin‐echo and gradient‐echo sequences. The diagnostic efficacy of OMP was examined by comparing pre‐ and postcontrast images. Bowel loops and abdominal organs were more easily recognizable after OMP ingestion, and the general quality of the images was improved because of fewer bowel‐related artifacts. The diagnostic value of the postcontrast abdominal MR examination was superior or equal to that of the precontrast study, and additional information was obtained in 44% of the cases. Postcontrast gradient‐echo sequences increased confidence in the MR examination in 18% of cases. OMP was well tolerated and increased the quality and amount of diagnostic information acquired during the examination. Gradient‐echo imaging was found to be a useful complement, but the need for a reduction in susceptibility artifacts was apparent and indicates that a decrease in TE or the use of rapid spin‐echo sequences might be advantageous.

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