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Contrasting patterns and frequency of antibodies to the surface, core, and e antigens of hepatitis b virus in blood donors and in homosexual patients

✍ Scribed by R.S. Tedder; C.H. Cameron; Ruth Wilson-Croome; D.R. Howell; Anne Colgrove; J.A.J. Barbara

Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
606 KB
Volume
6
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

An attempt was made to assess the significance of the relatively frequent low‐titre positive reactions in radioimmunoassays for antibody to hepatitis B surface antigen.

Serum specimens negative for surface antigen were assayed for antibodies to the surface, core, and e antigens of the Hepatitis B virus.

Two populations were studied—one of low hepatitis B incidence (2000 blood donors) and one of high incidence (200 male patients attending a clinic for sexually transmitted diseases).

The validity of some singly occurring low‐titre anti‐HBs and anti‐HBc reactions is questioned, and the occurrence of positive reactions unrelated to previous hepatitis B infection inferred.

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