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Contrast sensitivity in Parkinson's disease patients with subthalamic nucleus deep brain stimulation

✍ Scribed by Kelvin L. Chou; Melissa M. Amick; Margaret Gagner

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
457 KB
Volume
24
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

This study examined whether deep brain stimulation (DBS) would affect the contrast sensitivity (CS) curve in patients with PD. CS was tested in 12 nondemented PD patients treated with bilateral subthalamic nucleus DBS on and off stimulation and medications. Neither stimulation condition (on vs. off) nor medications altered CS performance in this group of patients. However, collapsed across conditions, patients with bipolar stimulation in this study had significantly poorer CS at higher spatial frequencies (12 and 18 cycles per degree) than patients with monopolar stimulation. This suggests that CS deficits in PD may possibly be influenced by DBS polarity and merits further study. Β© 2009 Movement Disorder Society

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