𝔖 Bobbio Scriptorium
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Contrast agents for fast imaging

✍ Scribed by Gerald L. Wolf; Jadwiga Rogowska

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
259 KB
Volume
22
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Many new pulse sequences are available that can be completed in less time than conventional spin-echo MRI. However, an operational definition of "fast" is twice the speed of the (dynamic) process of interest. Adequate speed is necessary, but may not be sufficient. The imaging must also have satisfactory spatial resolution and safety and must report the signal of interest with sufficient reliability to be interpretable. Frequently, quantitative or semiquantitative measurements must be feasible, even when the outcome is only expressed relative to a control or compared to a previous assessment of the same parameter.

Contrary to earlier speculations, MR contrast agents have provided useful characterizations of tissue anatomy or function when utilized with slower imaging methods. The purpose of this paper is to examine some generalities that influence the utility of contrast agents when MR technology allows faster imaging. The measurement of tissue perfusion will serve as the illustrative example of the general principles.

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