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Contrast agents as a biological marker in magnetic resonance imaging of the liver: conventional and new approaches

✍ Scribed by Wieland H. Sommer; Steven Sourbron; Alexander Huppertz; Michael Ingrisch; Maximilian F. Reiser; Christoph J. Zech


Book ID
113026426
Publisher
Springer
Year
2011
Tongue
English
Weight
908 KB
Volume
37
Category
Article
ISSN
0942-8925

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The introduction of a lipophilic moiety into the gadolinium chelate Gd-DTPA (dimeglumine gadopentetate, Magnevist) yielded Gd-EOB-DTPA (short form), which has potential as a magnetic resonance contrast agent for liver mass screening. The pharmacokinetics of Gd-EOB-DTPA in rats is nonlinear because a