Contraceptive efficacy of Balanites roxburghii pericarp extract in male mice (Mus musculus)

✍ Scribed by M. V. Rao; K. D. Shah; M. Rajani

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 135 KB
• Volume: 11
• Category: Article
• ISSN: 0951-418X
• DOI: 10.1002/(sici)1099-1573(199709)11:6<469::aid-ptr135>3.0.co;2-5

✦ Synopsis

The effects of daily oral feeding of a crude alcohol extract from the pericarp of unripe fruits of Balanites roxburghii at a dose of 500 mg/kg for 45 days were investigated with respect to epididymal and testicular histophysiology, metabolism and the fertility potential of mice, following withdrawal study. The testicular and cauda epididymal parameters revealed altered physiology and metabolism resulting in a reduction in fertility of extract-fed mice. Moreover, the induced effects seemed to be transient and were reversible upon withdrawal, showing its antifertility action.