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Continuous twin screw granulation: Influence of process variables on granule and tablet quality

✍ Scribed by J. Vercruysse; D. Córdoba Díaz; E. Peeters; M. Fonteyne; U. Delaet; I. Van Assche; T. De Beer; J.P. Remon; C. Vervaet


Book ID
118037285
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
752 KB
Volume
82
Category
Article
ISSN
0939-6411

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The influence of different screw element types on wet granulation process with a twin-screw extruder was investigated. Lactose granules were prepared with different screw configurations such as conveying, combing mixer and kneading elements. The use of kneading blocks led to an almost complete agglo