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Continuous Molecular Evolution of Protein-Domain Structures by Single Amino Acid Changes

✍ Scribed by Sebastian Meier; Pernille R. Jensen; Charles N. David; Jarrod Chapman; Thomas W. Holstein; Stephan Grzesiek; Suat Özbek

Book ID
113560502
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
839 KB
Volume
17
Category
Article
ISSN
0960-9822

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## Abstract The adiabatic compressibility (β~__s__~) was determined, by means of the precise sound velocity and density measurements, for a series of single amino acid substituted mutant enzymes of __Escherichia coli__ dihydrofolate reductase (DHFR) and aspartate aminotransferase (AspAT). Interesti