Human lymphocytes that produce anti-pneumococcal antibodies were separated and immortalized by Epstein-Barr virus and then cloned. One clone (NAD-Sel) produces an IgA, kappa antibody which is specific for the polysaccharides of type 8 pneumococcus, while not reactive with any of the polysaccharides
Continuous in vitro production of IgA by a human colostral immortalized cell line
β Scribed by A. Avital; S. Tamir; M. Steinitz
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 331 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0165-2478
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A non-tumorigenic epithelial cell line designated PCIAA, derived from a large pre-malignant colorectal adenoma from a patient with familial polyposis coli (also referred to as hereditary adenomatosis of the colon and rectum) has become immortal in vitro. PCIAA has been passaged in vitro continuously
We have previously reported that continuous in vitro passage in the presence of 3T3 feeders of a non-tumorigenic adenoma-derived epithelial cell line, designated PCIAA, resulted in its becoming immortal. At early passage PCIAA was normal diploid, whereas every cell of PCIAA late passage had an isoch
The cells obtained from four established human colon carcinoma cell lines were cultured in soft agar in the presence of eight chemotherapeutic agents that have been used clinically in patients with metastatic colorectal carcinoma. 5-Fluorouracil, mitomycin C , adriamycin, and cis-platinum were highl
## Abstract Suppression subtractive hybridization (SSH) was applied to identify differentially expressed genes in the SV40LT immortalized human bronchial epithelial cell line YβBE, with normal human bronchial epithelial cells (HBEC) as a control. Two cDNA libraries of upβ and downregulated genes we