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Continuous flow-injection-atomic absorption spectrometric method for the determination of Ondansetron

✍ Scribed by L.Lahuerta Zamora; J.Martínez Calatayud

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
544 KB
Volume
300
Category
Article
ISSN
0003-2670

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✦ Synopsis

A flow-injection procedure for the indirect determination of the new drug Ondansetron is proposed. The method is based on the reaction of the drug in an oxidative solid-phase reactor included in the flow assembly. The reactor was made by lead dioxide physically entrapped by polymerization; the released lead( II) was monitored by atomic absorption spectrometry at 217.0 rmr. The procedure gave a linear calibration graph up to 20 pg ml-' of Ondansetron with a sample throughput of 338 samples h-'.

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