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Content of a cross-reactive idiotype in nonimmune A/J sera

✍ Scribed by Mary C. Barrett; Alfred Nisonoff

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
186 KB
Volume
12
Category
Article
ISSN
0014-2980

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✦ Synopsis

Abstract

The anti‐p‐azophenylarsonate antibodies of A/J mice express a major intrastrain cross‐reactive idiotype (CRI~A~). Using a sensitive radioimmunoassay we were unable to detect significant quantities of molecules bearing CRI~A~ in nonimmune A/J sera. The upper limit is 140 ng/ml. Possible reasons for variability of such data in the published literature are discussed.

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