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Construction of functionalised medium rings by stereospecific expansions of 2,3-epoxy alcohols under mild conditions
β Scribed by Charles M. Marson; Afzal Khan; Rod A. Porter; Alexander J.A. Cobb
- Book ID
- 104251784
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 104 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Stereospecific ring openings of optically active 2,3epoxy alcohols were performed by the reaction of 1, 3,5, and 7 with curbon disulfide and sodium hydride to give the five-membered xanthates 2, 4, 6, and 8. Both enantiomers of 2-mercapto-l,3-diol triacetates, 11 and 14, were derived from 4 and 6, r
Oxygen-Directed Carbocyclizations of 2,3-Epoxy Alcohols: Stereoselective Construction of Polyfunctionalized Seven-Membered Rings by 7-endo-Tet Ring Closures. -The first examples of alkyne-epoxy alcohol cyclizations that lead to seven-membered carbocyclic rings are reported together with the first co