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Asymmetric Construction of Quaternary Carbon Centers by Titanium-Mediated Stereospecific Allylation of 2,3-Epoxy Alcohol Derivatives.

โœ Scribed by Hiroaki Ohno; Kei Hiramatsu; Tetsuaki Tanaka


Book ID
101958975
Publisher
John Wiley and Sons
Year
2004
Weight
127 KB
Volume
35
Category
Article
ISSN
0931-7597

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Construction of chiral quaternary carbon
โœ Yasuhiro Yamashita; Kazunori Odashima; Kenji Koga ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 217 KB

Enantioselective asymmetric alkylation of achiral lithium enolates mediated by chiral tetradentate amine ligands is achieved to give chiral quaternary carbon centers. Turnover of a chiral tetradentate amine in the presence of an achiral bidentate amine during the reaction is also realized.