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Construction of cis - and trans -Decahydroisoquinolines via Heterogeneous Catalytic Hydrogenation

✍ Scribed by MaGee, David I.; Lee, May Ling; Decken, Andreas

Book ID
127357100
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
72 KB
Volume
64
Category
Article
ISSN
0022-3263

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Construction of cis- and trans-octahydro
Construction of cis- and trans-octahydroisoquinoline-7-ones via a tandem ring-opening and -closing strategy
✍ David I MaGee; May Ling Lee πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 71 KB

cis-and trans-Octahyroisoquinolines can be efficiently constructed via a tandem ring-opening and -closing strategy. The precursors required to achieve this transformation are easily obtained by a Diels-Alder reaction followed by a stereoselective hydrogenation.