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Construction of cis- and trans-octahydroisoquinoline-7-ones via a tandem ring-opening and -closing strategy

✍ Scribed by David I MaGee; May Ling Lee

Book ID
104231521
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
71 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

cis-and trans-Octahyroisoquinolines can be efficiently constructed via a tandem ring-opening and -closing strategy. The precursors required to achieve this transformation are easily obtained by a Diels-Alder reaction followed by a stereoselective hydrogenation.

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