Construction of Chiral Tertiary Alcohol
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Yang, Hua; Sun, Moran; Zhao, Shuguang; Zhu, Ming; Xie, Yangla; Niu, Changling; L
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Article
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2012
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American Chemical Society
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English
β 645 KB
For the first time, the [2,3]-Meisenheimer rearrangement has been developed into a general strategy for the construction of chiral tertiary alcohols. The effectiveness and practicality of this methodology are illustrated by the successful synthesis of (R)-20 and (R)-30, the side chain acids of homoh