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Construction of adiponectin-encoding plasmid DNA and overexpression in mice in vivo

โœ Scribed by Yan-Na Huang; Jian-Hua Qi; Lan Xiang; Yi-Zhen Wang

Book ID
116508882
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
1004 KB
Volume
502
Category
Article
ISSN
0378-1119

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To examine the effects of inflammatory response to plasmid DNA (pDNA) on transgene expression, serum tumor necrosis factor-a (TNF-a) was measured after intravenous injection of pDNA or calf thymus DNA (CT DNA) in the naked or complexed form with cationic liposomes (lipoplex). pDNA with many CpG moti